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Rune unlock priority for fast farming

~4 min read·Reviewed v1.00.08·Updated 2026-06-02

Why drop chance first

Every other progression mechanic — gear, materials, Cube fuel — feeds off drops. A +20% Drop Chance Normal Chest rune compounds 1.2× across every chest you'll open for the rest of the game. Compound is king.

Inventory slot

When inventory fills, the game stops giving you drops until you alchemize or sell. A +N slot rune buys you tens of seconds back per session — adds up fast.